Tag Archives: aging

Running-induced gum line improvements and implications – #fitness #longevity #lifespan #running #aging #exercise #nutrition #biking #carfree #runners #polyphenols #polyphenol #health #flavonoids #nfat

I was abit shocked the other day to find some improvement along the gum line, so checked… http://bit.ly/183Qu7s . It’s no surprise that running would improve gum lines. Many of you will probably know that gum health is predictive for cardiovascular disease. The gums were already exceptionally healthy, which is why I was so shocked by the improvement. Running works. People used to say that the gums could not be regenerated. We now know better. There are some reports of gum soreness from running, but it is likely transient, and some adverse microorganisms probably can’t hack the training. Immune withdrawal and changes in the microflora also likely explain some of this discomfort. I’d suggest some disinfectant mouthwash. Massage it into the gum line with your tongue.
They are still studying the correlation between gum line and system inflammation: Clin Chim Acta:Degree of gingivitis correlates to systemic inflammation… It reminds me of the warnings that we have had about systemic inflammation, but also of NSAID and COXIB abuse. One would infer then that running reduces systemic inflammation. CR aficionados might recognize this – Cyclosporine-induced gingival overgrowth correlates with NFAT-reg… According to Wikipedia,”NFAT is also involved in the development of cardiac, skeletal muscle”. One supposes that physical activity suppresses NFAT in T-cells to reduce free radical load. Essentially, running would reduce adverse immune invasion in the gum line. and in other places as well, which explains many of the pleasant effects. This is also likely related to the beneficial adaptations in cardiac and skeletal muscle, and opposed to aberrant remodeling, such as fibrosis. It is not difficult to imagine how the CR-memetic flavonoids and polyphenols might amplify this beneficial effect of running. These molecules are known to affect NFAT activity.

Adverse immune invasion is coming to the forefront as one of the primary effects of aging. The effect of running and these molecules gladly appears to be ADDITIVE in this case. One of the great things about running is what it teaches you about the difference between pain and discomfort. Avoid abuse of painkillers. Less inflammatory load means that runners may need less aspirin and other painkillers, not more.

More cold weather training notes – #fitness #running #biking #exercise #lifespan #fasting #aging


Last night my toes were numb. Today, I feel hearty. Go figure. Happy winter! I also noticed the vibration in the fingers this morning. This is good progress. It would be worth looking at the frequency of the vibration, which is similar to shivering vibration and tongue trill. People also say you can get a taste of this, as it were, from szechuan peppers, which can also produce numbness. These peppers are ironically noted for their heat, but they are overloading the channels that are related to cold sensation. It was in the low 20s F. I also noticed the hills were a good remedy for sleepiness. Breathe harder.
Clearly, there is more to the numbness and sleepy sensations than just the channels. 😉 Increased urgency is also consistent with the benzoate derivatives theory. Cold produces more incomplete metabolic products. Darned irritating, especially on a bicycle, where there is more pressure on the bladder. I enjoyed a hot breakfast this morning, very much.
The feet stay sore longer in the cold. I was reminded my feet are mildly supinated, which probably explains why I'm running again, but so late in life. It's really a proverb. Nice thing about this situation is that I can bring a lifetime of biochemical study to the pursuit.

Here are the experiments. You can prove it to yourself. – #aging #biking #carfree #Exercise #fasting #fitness #lifespan #longevity #nutrition #running #training


Read the calorie labels, including the pet food. Weigh your pets. The calculation is really easy. Put more food in the dish than your animal will eat in a day. Weigh the dish before and after, and subtract. Divide the calories per day by the animal's weight,&do the same thing for all your pets, and yourself too. Behold your numbers! If you like numbers, it's easy to calculate the extra calorie calorie burn in freezing weather. Look up average thermogenics at room temp. There is zero thermogenic calorie burn at body temperature. Put the numbers on a graph, and draw a line to freezing temperature. I think that people will be pretty surprised by these numbers. After you've done these two things, the calorie numbers in the fitness trackers will make more sense. The third experiment is to measure your weight loss per day on an extended fast. Calculate the calories. Advanced folks can use a fat meter to debunk the 3000 calorie myth.

More Interval Fasting Notes – #fasting #fitness #running #biking #exercise #carfree #training #nutrition #longevity #lifespan #aging


It looks like fasting intervals can sum up to about 12 days per month. I don't recommend going all the way to 15 days. Even half of that should bring some benefit. Nice thing about intervals, a person should be able to start low and work up to it. For example, if you managed to fast twice for three days each month, this would be comparable to 20% calorie restriction. Like a workout, you could piece intervals together. I had to break my fast early this weekend, so I'm fasting again next weekend. It is intermittent fasting for fitness buffs. The intermittent fasting folks say that you can eat as much as you want in between fasts and still get the same benefit. Athletic types can fast without worrying that they are running too short of calories. For extended fasts, two week recovery condition applies at this time. Be safe. Nice thing about fasting recovery interval is that you can still workout. In fact, working out is recommended throughout.
Some may look at these calorie numbers and say that the program is to strenuous, but short-term fasting does not produce physical damage, so that a heavier calorie load is possible during fasting than during physical activity. 
What is an extended fast? It's like an extended workout. Fasting 3 days or more burns several thousand calories, which is comparable to running a marathon or biking a centuray ride. I was thrilled by the improvement in my running time after my last extended fast. Fasting is the athlete's secret.

Interval Fasting – #fasting #biking #running #aging #lifespan #exercise #fitness #nutrition #longevity

A fasting man of average size will lose about 1500 calories of body weight each day. 1500 calories is equal to about 1 lb of body weight, biking for about 3 hours, or running 4 hours. I’ve noticed that fasting is alot like extreme training except you don’t get winded. Fasting makes a person tired in a similar way as hard work. Fasted muscles may be a little slow and crampy for this reason. It is alot like the after effects of exercise. These observations probably explain why is fasting better than exercise from a longevity perspective, although you really need both exercise and fasting.
Fasting gives a similar effect as exercise, but without the high oxygen exposure. It should be possible to better isolate the beneficial effects by thinking about the comparison of fasting and exercise. In this round of fasting I lost weight faster than in previous rounds, which can only be due to improved conditioning over the past years. Endurance training improves the capacity to store energy.
After fasting two days, the next morning I got my best running time ever. It would actually be a good idea, to get an estimate of improved muscle conditioning from the higher rate of weight loss during fasting. I did a little calculation. The faster time is apparently directly related to the weight loss, so this result is ambiguous, but there’s also an incentive.
The lore says that fasting is easier in the cooler months. Why not get an early start before the holidays. You can fast for peace ;-). After fasting over 3 days I realized that fasting a well-conditioned body really does result in more cramps. I also woke up with minor stinging in the calves. It is easy to conclude that the difference may be a shift in metabolic rate. The cramps went away immediately, when I broke fast. The minor stinging was resolved with a few stretch/flexes. Later that day, I broke my fast. It may be possible to speed the release of energy stores by combining exercise and fasting. The effect of this combination was manageable, and I realized that I might have gone running instead of breaking my fast.
It is not yet clear whether the combined regimen led to the increased cramping on the 4th day of the fast. Next experiment is whether additional bouts of combined fasting and exercise will eliminate the cramps. The model suggests a recovery period of 2-3 days should be sufficient, but there is also a barrier to initiating a fast. Fasting intervals could be delayed some additional days to reduce any resultant muscle loss. Of course, the muscle loss is easily reversible, and the benefits of fasting are now plainly evident. If you undertake this program, make sure to include supplementation to get the full benefit. Happy fasting!
Update: One more thing to note about interval fasting. It will likely waste your body, if you do not combine with healthy diet and exercise.  I recommend using a fitness tracker to calculate the required calorie consumption for your level of fitness training.